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Laura Jana
Penn State University's Prevention Research Center
September 2015
Anyone working on/aware of new device(s) for POC diagnosis of tuberculosis?
< 1 min reading time

I am particularly interested to learn whether anyone in this group has tackled the challenge of (or is aware of) any new point of care devices that are able to diagnose tuberculosis (in particular, multi-drug-resistant tb) in a way that is more efficient and cost effective than current PCR or culturing. If so – definitely want to hear about it and happy to share details about potential opportunity. If not, them perhaps we as a group might want to consider why….clearly MDR TB is of huge global significance, and wide-scale reliance on PCR and/or cultures in this day and age of tech-driven medical innovation seems a bit unrealistic (not to mention slow and expensive)!

source: https://www.linkedin.com/groups/78665/78665-6044643809101434883

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Posted by Laura Jana
Asked on September 2, 2015 8:00 am
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I'll forward your request to a company I know
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Laura Jana Thanks very much Caroline - hoping it might be a really good opportunity for any company focusing in on this!
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Laura...I may know of a potential lead, but have a couple questions. Feel free to message me. Best, John
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Hi Laura. I am CEO of GBDbio. We are developing a low-cost, biosafe, rapid TB test and I would love to chat further with you. We are commercializing technology originally funded by the Gates Foundation to Texas A&M and Stanford. Our company was formed to commercialize this technology and we have been at it since 2009. Our major funding has come from the Wellcome Trust and the Foundation for Innovative New Diagnostics, as well as 1 venture round led by two social impact funds. Please see our website (www.gbdbio.com) for more information!
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Laura Jana Thanks very much Arthur - appreciate the links as reference. Was looking for quick connect(s) as I know of a potential, fully-funded opportunity to field test/evaluate! Thanks to group for helpful responses/intros
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You should have a look at Cepheid's website for the new Omni POC device to run the Xpert MTB assay.
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"Laura, there are so many... A google search for "Point of care diagnostics" "Tuberculosis" turns up 28.000 hits!

A good article on the challenges and what's coming is at http://www.omicsonline.org/open-access/point-of-care-diagnostics-for-tuberculosis-are-we-there-2161-1068.1000e124.php?aid=23304

WHO thinks that POC may start to get traction this year, but they are still focussing on traditional labs. See http://www.who.int/tb/laboratory/en/

Arthur

Arthur
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Quidel Savannah, Alere q, and QuantuMDx are all very promising TB diagnostics in late stage development both for moderate complexity and POC.
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Stella S. I don't know about you but I, along with many, many others can tell when someone has TB just by the color of their skin and the tint (color) of the whites of their eyes as early as 2.5 to 3 weeks after contagion. And...with all the illegal immigrants, you must learn to do this by speaking to an MD who is a specialist in TB, since you can catch it just by being face to face within 2 feet of them and talking to them or accidentally breathing the air they exhale!
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Bogdan Baudis http://medicalphysicsweb.org/cws/article/newsfeed/65555
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